Considering the APOE locus in Alzheimer’s disease polygenic scores in the Health and Retirement Study: a longitudinal panel study

BACKGROUND: Polygenic scores are a strategy to aggregate the small, additive effects of single nucleotide polymorphisms across the genome. With phenotypes like Alzheimer’s disease, which have a strong and well-established genomic locus (APOE), the cumulative effect of genetic variants outside of thi...

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Detalles Bibliográficos
Autores principales: Ware, Erin B., Faul, Jessica D., Mitchell, Colter M., Bakulski, Kelly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607711/
https://www.ncbi.nlm.nih.gov/pubmed/33143703
http://dx.doi.org/10.1186/s12920-020-00815-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7607711/
https://www.ncbi.nlm.nih.gov/pubmed/33143703
http://dx.doi.org/10.1186/s12920-020-00815-9

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