Genipin enhances the antitumor effect of elesclomol in A549 lung cancer cells by blocking uncoupling protein-2 and stimulating reactive oxygen species production

The uncoupling protein-2 (UCP2) serves a role in tumor aggressiveness and anticancer resistance, which is considered to be associated with its ability to attenuate reactive oxygen species (ROS) production. We hypothesized that UCP2 may protect cancer cells from elesclomol-induced cytotoxicity, and t...

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Detalles Bibliográficos
Autores principales: Lee, Jin Hee, Cho, Young Seok, Jung, Kyung-Ho, Park, Jin Won, Lee, Kyung-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608048/
https://www.ncbi.nlm.nih.gov/pubmed/33154772
http://dx.doi.org/10.3892/ol.2020.12237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608048/
https://www.ncbi.nlm.nih.gov/pubmed/33154772
http://dx.doi.org/10.3892/ol.2020.12237

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