Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint

Local phosphatase regulation is needed at kinetochores to silence the mitotic checkpoint (a.k.a. spindle assembly checkpoint [SAC]). A key event in this regard is the dephosphorylation of MELT repeats on KNL1, which removes SAC proteins from the kinetochore, including the BUB complex. We show here t...

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Detalles Bibliográficos
Autores principales: Cordeiro, Marilia H., Smith, Richard J., Saurin, Adrian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608062/
https://www.ncbi.nlm.nih.gov/pubmed/33125045
http://dx.doi.org/10.1083/jcb.202002020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608062/
https://www.ncbi.nlm.nih.gov/pubmed/33125045
http://dx.doi.org/10.1083/jcb.202002020

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