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Type I interferon signaling mediates Mycobacterium tuberculosis–induced macrophage death

Macrophages help defend the host against Mycobacterium tuberculosis (Mtb), the major cause of tuberculosis (TB). Once phagocytized, Mtb resists killing by macrophages, replicates inside them, and leads to their death, releasing Mtb that can infect other cells. We found that the death of Mtb-infected...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Jiang, Xiuju, Pfau, Daniel, Ling, Yan, Nathan, Carl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608065/
https://www.ncbi.nlm.nih.gov/pubmed/33125053
http://dx.doi.org/10.1084/jem.20200887