miR-155 promotes T reg cell development by safeguarding medullary thymic epithelial cell maturation

During thymocyte development, medullary thymic epithelial cells (mTECs) provide appropriate instructive cues in the thymic microenvironment for not only negative selection but also the generation of regulatory T (T reg) cells. Here, we identify that miR-155, a microRNA whose expression in T reg cell...

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Detalles Bibliográficos
Autores principales: Dong, Jiayi, Warner, Lindsey M., Lin, Ling-Li, Chen, Mei-Chi, O'Connell, Ryan M., Lu, Li-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608066/
https://www.ncbi.nlm.nih.gov/pubmed/33125052
http://dx.doi.org/10.1084/jem.20192423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608066/
https://www.ncbi.nlm.nih.gov/pubmed/33125052
http://dx.doi.org/10.1084/jem.20192423

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