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sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway

Doxorubicin (Dox) is an effective chemotherapy drug against a wide range of cancers, including both hematological and solid tumors. However, the serious cardiotoxic effect restricted its clinical application. We previously have illuminated the protective role of canonical Wnt/β-catenin signaling in...

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Detalles Bibliográficos
Autores principales: Hu, Yue-huai, Liu, Jie, Lu, Jing, Wang, Pan-xia, Chen, Jian-xing, Guo, Ying, Han, Fang-hai, Wang, Jun-jian, Li, Wei, Liu, Pei-qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608092/
https://www.ncbi.nlm.nih.gov/pubmed/32238888
http://dx.doi.org/10.1038/s41401-020-0364-z