Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization

Keloid is a benign skin tumor characterized by its cell hyperproliferative activity, invasion into normal skin, uncontrolled growth, overproduction and deposition of extracellular matrices and high recurrence rate after various therapies. Nintedanib is a receptor tyrosine kinase inhibitor targeting...

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Detalles Bibliográficos
Autores principales: Zhou, Bo-ya, Wang, Wen-bo, Wu, Xiao-li, Zhang, Wen-jie, Zhou, Guang-dong, Gao, Zhen, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608201/
https://www.ncbi.nlm.nih.gov/pubmed/32327724
http://dx.doi.org/10.1038/s41401-020-0381-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608201/
https://www.ncbi.nlm.nih.gov/pubmed/32327724
http://dx.doi.org/10.1038/s41401-020-0381-y

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