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The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease

Mammary and extramammary Paget’s Diseases (PD) are a malignant skin cancer characterized by the appearance of Paget cells. Although easily diagnosed, its pathogenesis remains unknown. Here, single-cell RNA-sequencing identified distinct cellular states, novel biomarkers, and signaling pathways — inc...

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Detalles Bibliográficos
Autores principales: Song, Yongli, Guerrero-Juarez, Christian F., Chen, Zhongjian, Tang, Yichen, Ma, Xianghui, Lv, Cong, Bi, Xueyun, Deng, Min, Bu, Lina, Tian, Yuhua, Liu, Ruiqi, Zhao, Ran, Xu, Jiuzhi, Sheng, Xiaole, Du, Sujuan, Liu, Yeqiang, Zhu, Yunlu, Shan, Shi-jun, Chen, Hong-duo, Zhao, Yiqiang, Zhou, Guangbiao, Shuai, Jianwei, Ren, Fazheng, Xue, Lixiang, Ying, Zhaoxia, Dai, Xing, Lengner, Christopher J., Andersen, Bogi, Plikus, Maksim V., Nie, Qing, Yu, Zhengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608215/
https://www.ncbi.nlm.nih.gov/pubmed/32457396
http://dx.doi.org/10.1038/s41422-020-0334-5