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Inflammasome genetics and complex diseases: a comprehensive review

The inflammasome is a cytoplasmic multiprotein complex responsible for the activation of inflammatory caspases (caspase-1, -4, and -5) in response to pathogen- and/or damage-associated molecular patterns or to homeostasis-altering molecular pathways, and for the consequent release of the pro-inflamm...

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Detalles Bibliográficos
Autores principales: Fernandes, Fernanda Pereira, Leal, Vinicius N. C., Souza de Lima, Dhemerson, Reis, Edione C., Pontillo, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608315/
https://www.ncbi.nlm.nih.gov/pubmed/32499599
http://dx.doi.org/10.1038/s41431-020-0631-y