Ritanserin blocks Ca(V)1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies

Ca(V)1.2 channel blockers or 5-HT(2) receptor antagonists constitute effective therapy for Raynaud’s syndrome. A functional link between the inhibition of 5-HT(2) receptors and Ca(V)1.2 channel blockade in arterial smooth muscles has been hypothesized. Therefore, the effects of ritanserin, a nonsele...

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Detalles Bibliográficos
Autores principales: Fusi, Fabio, Trezza, Alfonso, Sgaragli, Giampietro, Spiga, Ottavia, Saponara, Simona, Bova, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608335/
https://www.ncbi.nlm.nih.gov/pubmed/32132658
http://dx.doi.org/10.1038/s41401-020-0370-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608335/
https://www.ncbi.nlm.nih.gov/pubmed/32132658
http://dx.doi.org/10.1038/s41401-020-0370-1

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