Cargando…
Ritanserin blocks Ca(V)1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies
Ca(V)1.2 channel blockers or 5-HT(2) receptor antagonists constitute effective therapy for Raynaud’s syndrome. A functional link between the inhibition of 5-HT(2) receptors and Ca(V)1.2 channel blockade in arterial smooth muscles has been hypothesized. Therefore, the effects of ritanserin, a nonsele...
Autores principales: | Fusi, Fabio, Trezza, Alfonso, Sgaragli, Giampietro, Spiga, Ottavia, Saponara, Simona, Bova, Sergio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608335/ https://www.ncbi.nlm.nih.gov/pubmed/32132658 http://dx.doi.org/10.1038/s41401-020-0370-1 |
Ejemplares similares
-
The Selective Rat Toxicant Norbormide Blocks K(ATP) Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells
por: Saponara, Simona, et al.
Publicado: (2019) -
From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel
por: Trezza, Alfonso, et al.
Publicado: (2018) -
Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits Ca(V)1.2 and Stimulates K(Ca)1.1 Channels
por: Carullo, Gabriele, et al.
Publicado: (2022) -
Vietnamese Dalbergia tonkinensis: A Promising Source of Mono- and Bifunctional Vasodilators
por: Cuong, Nguyen Manh, et al.
Publicado: (2022) -
3,5-Di-t-butyl catechol (DTCAT) as an activator of the human skeletal muscle ryanodine receptor Ca(2+ )channel and its evaluation as a test substance for the assessment of susceptibility to malignant hyperthermia
por: Lacava, Caterina, et al.
Publicado: (2009)