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The exhaustive genomic scan approach, with an application to rare-variant association analysis

Region-based genome-wide scans are usually performed by use of a priori chosen analysis regions. Such an approach will likely miss the region comprising the strongest signal and, thus, may result in increased type II error rates and decreased power. Here, we propose a genomic exhaustive scan approac...

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Detalles Bibliográficos
Autores principales: Kanoungi, George, Nothnagel, Michael, Becker, Tim, Drichel, Dmitriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608423/
https://www.ncbi.nlm.nih.gov/pubmed/32415273
http://dx.doi.org/10.1038/s41431-020-0639-3