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The exhaustive genomic scan approach, with an application to rare-variant association analysis
Region-based genome-wide scans are usually performed by use of a priori chosen analysis regions. Such an approach will likely miss the region comprising the strongest signal and, thus, may result in increased type II error rates and decreased power. Here, we propose a genomic exhaustive scan approac...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608423/ https://www.ncbi.nlm.nih.gov/pubmed/32415273 http://dx.doi.org/10.1038/s41431-020-0639-3 |