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RIP1 promotes proliferation through G2/M checkpoint progression and mediates cisplatin-induced apoptosis and necroptosis in human ovarian cancer cells

Receptor-interacting protein 1 (RIP1, also known as RIPK1) is not only a tumor-promoting factor in several cancers but also mediates either apoptosis or necroptosis in certain circumstances. In this study we investigated what role RIP1 plays in human ovarian cancer cells. We showed that knockout (KO...

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Detalles Bibliográficos
Autores principales: Zheng, Xue-lian, Yang, Jiao-jiao, Wang, Yan-yun, Li, Qin, Song, Ya-ping, Su, Min, Li, Jin-ke, Zhang, Lin, Li, Zhi-ping, Zhou, Bin, Lin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608477/
https://www.ncbi.nlm.nih.gov/pubmed/32242118
http://dx.doi.org/10.1038/s41401-019-0340-7