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Human Spermatogenesis Tolerates Massive Size Reduction of the Pseudoautosomal Region

Mammalian male meiosis requires homologous recombination between the X and Y chromosomes. In humans, such recombination occurs exclusively in the short arm pseudoautosomal region (PAR1) of 2.699 Mb in size. Although it is known that complete deletion of PAR1 causes spermatogenic arrest, no studies h...

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Detalles Bibliográficos
Autores principales: Fukami, Maki, Fujisawa, Yasuko, Ono, Hiroyuki, Jinno, Tomoko, Ogata, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608489/
https://www.ncbi.nlm.nih.gov/pubmed/32785664
http://dx.doi.org/10.1093/gbe/evaa168