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Down-Regulation of NOX4 Expression in Dorsal Horn of Spinal Cord Could Alleviate Cancer-Induced Bone Pain in Rats by Reducing Oxidative Stress Response

INTRODUCTION: Cancer-induced bone pain (CIBP) is very common in patients with advanced cancer. Recent studies have shown that reactive oxygen species (ROS) can sense and regulate pain response process through spinal cord mechanism, and play a role in CIBP. NADPH oxidase (NOX) is a group of protease...

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Detalles Bibliográficos
Autores principales: Long, Hao, Zheng, Hui, Ai, Long, Osman, Kamil, Liu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608490/
https://www.ncbi.nlm.nih.gov/pubmed/33154672
http://dx.doi.org/10.2147/CMAR.S263177