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Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART

The HIV-1 reservoir is the major hurdle to curing HIV-1. However, the impact of the viral genome on the HIV-1 reservoir, i.e. its heritability, remains unknown. We investigate the heritability of the HIV-1 reservoir size and its long-term decay by analyzing the distribution of those traits on viral...

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Detalles Bibliográficos
Autores principales: Wan, Chenjie, Bachmann, Nadine, Mitov, Venelin, Blanquart, François, Céspedes, Susana Posada, Turk, Teja, Neumann, Kathrin, Beerenwinkel, Niko, Bogojeska, Jasmina, Fellay, Jacques, Roth, Volker, Böni, Jürg, Perreau, Matthieu, Klimkait, Thomas, Yerly, Sabine, Battegay, Manuel, Walti, Laura, Calmy, Alexandra, Vernazza, Pietro, Bernasconi, Enos, Cavassini, Matthias, Metzner, Karin J., Günthard, Huldrych F., Kouyos, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608612/
https://www.ncbi.nlm.nih.gov/pubmed/33139735
http://dx.doi.org/10.1038/s41467-020-19198-7