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Cleavable hairpin beacon-enhanced fluorescence detection of nucleic acid isothermal amplification and smartphone-based readout

Fluorescence detection of nucleic acid isothermal amplification utilizing energy-transfer-tagged oligonucleotide probes provides a highly sensitive and specific method for pathogen detection. However, currently available probes suffer from relatively weak fluorescence signals and are not suitable fo...

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Detalles Bibliográficos
Autores principales: Ding, Xiong, Yin, Kun, Li, Ziyue, Pandian, Vikram, Smyth, Joan A., Helal, Zeinab, Liu, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608614/
https://www.ncbi.nlm.nih.gov/pubmed/33139727
http://dx.doi.org/10.1038/s41598-020-75795-y