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Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Large portions of eukaryotic genomes consist of transposable elements (TEs), and the establishment of transcription-repressing heterochromatin during early development safeguards genome integrity in Drosophila. Repeat-rich Y chromosomes can act as reservoirs for TEs (‘toxic’ Y effect), and incomplet...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608633/ https://www.ncbi.nlm.nih.gov/pubmed/33139741 http://dx.doi.org/10.1038/s41467-020-19134-9 |