Cargando…
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
Large portions of eukaryotic genomes consist of transposable elements (TEs), and the establishment of transcription-repressing heterochromatin during early development safeguards genome integrity in Drosophila. Repeat-rich Y chromosomes can act as reservoirs for TEs (‘toxic’ Y effect), and incomplet...
Autores principales: | Wei, Kevin H.-C., Gibilisco, Lauren, Bachtrog, Doris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608633/ https://www.ncbi.nlm.nih.gov/pubmed/33139741 http://dx.doi.org/10.1038/s41467-020-19134-9 |
Ejemplares similares
-
De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture
por: Mahajan, Shivani, et al.
Publicado: (2018) -
Toxic Y chromosome: Increased repeat expression and age-associated heterochromatin loss in male Drosophila with a young Y chromosome
por: Nguyen, Alison H., et al.
Publicado: (2021) -
Alternative Splicing within and between Drosophila Species, Sexes, Tissues, and Developmental Stages
por: Gibilisco, Lauren, et al.
Publicado: (2016) -
Ancestral male recombination in Drosophila albomicans produced geographically restricted neo-Y chromosome haplotypes varying in age and onset of decay
por: Wei, Kevin H-C., et al.
Publicado: (2019) -
Recurrent gene co-amplification on Drosophila X and Y chromosomes
por: Ellison, Christopher, et al.
Publicado: (2019)