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Chiral phosphoric acid-catalyzed stereodivergent synthesis of trisubstituted allenes and computational mechanistic studies

Chiral molecules with multiple stereocenters are widely present in natural products and pharmaceuticals, whose absolute and relative configurations are both critically important for their physiological activities. In spite of the fact that a series of ingenious strategies have been developed for asy...

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Detalles Bibliográficos
Autores principales: Wang, Jiawen, Zheng, Sujuan, Rajkumar, Subramani, Xie, Jinglei, Yu, Na, Peng, Qian, Yang, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608664/
https://www.ncbi.nlm.nih.gov/pubmed/33139734
http://dx.doi.org/10.1038/s41467-020-19294-8