The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations

The ASCC3 subunit of the activating signal co-integrator complex is a dual-cassette Ski2-like nucleic acid helicase that provides single-stranded DNA for alkylation damage repair by the α-ketoglutarate-dependent dioxygenase AlkBH3. Other ASCC components integrate ASCC3/AlkBH3 into a complex DNA repa...

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Detalles Bibliográficos
Autores principales: Jia, Junqiao, Absmeier, Eva, Holton, Nicole, Pietrzyk-Brzezinska, Agnieszka J., Hackert, Philipp, Bohnsack, Katherine E., Bohnsack, Markus T., Wahl, Markus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608686/
https://www.ncbi.nlm.nih.gov/pubmed/33139697
http://dx.doi.org/10.1038/s41467-020-19221-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608686/
https://www.ncbi.nlm.nih.gov/pubmed/33139697
http://dx.doi.org/10.1038/s41467-020-19221-x

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