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The alternative macrophage relay: STAT6 passes the baton to EGR2

Alternative polarization of macrophages induced by IL-4 is important for homeostasis and tissue repair. Downstream from IL-4 receptor signaling, STAT6 activation is transient, but induces stable transcriptional changes. These data suggest that STAT6 induces second messengers to carry out the alterna...

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Detalles Bibliográficos
Autores principales: Liao, Jingwen, Hargreaves, Diana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608745/
https://www.ncbi.nlm.nih.gov/pubmed/33872194
http://dx.doi.org/10.1101/gad.345140.120