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Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia

Endogenous DNA double-strand breaks (DSBs) formation and repair in neural stem/progenitor cells (NSPCs) play fundamental roles in neurogenesis and neurodevelopmental disorders. NSPCs exhibit heterogeneity in terms of lineage fates and neurogenesis activity. Whether NSPCs also have heterogeneous regu...

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Detalles Bibliográficos
Autores principales: Li, Jingzheng, Shang, Yafang, Wang, Lin, Zhao, Bo, Sun, Chunli, Li, Jiali, Liu, Siling, Li, Cong, Tang, Min, Meng, Fei-Long, Zheng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608785/
https://www.ncbi.nlm.nih.gov/pubmed/33115731
http://dx.doi.org/10.1126/sciadv.aba0682