Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis

Formation of autoantibodies to carbamylated proteins (anti-CarP) is considered detrimental in the prognosis of erosive rheumatoid arthritis (RA). The source of carbamylated antigens and the mechanisms by which anti-CarP antibodies promote bone erosion in RA remain unknown. Here, we find that neutrop...

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Detalles Bibliográficos
Autores principales: O’Neil, Liam J., Barrera-Vargas, Ana, Sandoval-Heglund, Donavon, Merayo-Chalico, Javier, Aguirre-Aguilar, Eduardo, Aponte, Angel M., Ruiz-Perdomo, Yanira, Gucek, Marjan, El-Gabalawy, Hani, Fox, David A., Katz, James D., Kaplan, Mariana J., Carmona-Rivera, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608797/
https://www.ncbi.nlm.nih.gov/pubmed/33115748
http://dx.doi.org/10.1126/sciadv.abd2688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608797/
https://www.ncbi.nlm.nih.gov/pubmed/33115748
http://dx.doi.org/10.1126/sciadv.abd2688

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