K(2P) channel C-type gating involves asymmetric selectivity filter order-disorder transitions

K(2P) potassium channels regulate cellular excitability using their selectivity filter (C-type) gate. C-type gating mechanisms, best characterized in homotetrameric potassium channels, remain controversial and are attributed to selectivity filter pinching, dilation, or subtle structural changes. The...

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Detalles Bibliográficos
Autores principales: Lolicato, Marco, Natale, Andrew M., Abderemane-Ali, Fayal, Crottès, David, Capponi, Sara, Duman, Ramona, Wagner, Armin, Rosenberg, John M., Grabe, Michael, Minor, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608817/
https://www.ncbi.nlm.nih.gov/pubmed/33127683
http://dx.doi.org/10.1126/sciadv.abc9174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608817/
https://www.ncbi.nlm.nih.gov/pubmed/33127683
http://dx.doi.org/10.1126/sciadv.abc9174

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