Mycobacterial EST12 activates a RACK1–NLRP3–gasdermin D pyroptosis–IL-1β immune pathway

Pyroptosis, an inflammatory form of programmed cell death, has been implicated in eliminating pathogenic infections. However, macrophage pyroptosis–related proteins from Mycobacterium tuberculosis (M.tb) have largely gone unexplored. Here, we identified a cell pyroptosis–inducing protein, Rv1579c, n...

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Detalles Bibliográficos
Autores principales: Qu, Zilu, Zhou, Jin, Zhou, Yidan, Xie, Yan, Jiang, Yanjing, Wu, Jian, Luo, Zuoqin, Liu, Guanghui, Yin, Lei, Zhang, Xiao-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608829/
https://www.ncbi.nlm.nih.gov/pubmed/33097533
http://dx.doi.org/10.1126/sciadv.aba4733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608829/
https://www.ncbi.nlm.nih.gov/pubmed/33097533
http://dx.doi.org/10.1126/sciadv.aba4733

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