Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio

Externally deposited eggs begin development with an immense cytoplasm and a single overwhelmed nucleus. Rapid mitotic cycles restore normality as the ratio of nuclei to cytoplasm (N/C) increases. A threshold N/C has been widely proposed to activate zygotic genome transcription and onset of morphogen...

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Detalles Bibliográficos
Autores principales: Strong, Isaac J. T., Lei, Xiaoyun, Chen, Fang, Yuan, Kai, O’Farrell, Patrick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608951/
https://www.ncbi.nlm.nih.gov/pubmed/33090988
http://dx.doi.org/10.1371/journal.pbio.3000891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608951/
https://www.ncbi.nlm.nih.gov/pubmed/33090988
http://dx.doi.org/10.1371/journal.pbio.3000891

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