Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes

Telomeres are DNA-protein structures at the ends of chromosomes essential in maintaining chromosomal stability. Observational studies have identified associations between telomeres and elevated cancer risk, including hematologic malignancies; but biologic mechanisms relating telomere length to cance...

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Detalles Bibliográficos
Autores principales: Brown, Derek W., Lin, Shu-Hong, Loh, Po-Ru, Chanock, Stephen J., Savage, Sharon A., Machiela, Mitchell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608979/
https://www.ncbi.nlm.nih.gov/pubmed/33090998
http://dx.doi.org/10.1371/journal.pgen.1009078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608979/
https://www.ncbi.nlm.nih.gov/pubmed/33090998
http://dx.doi.org/10.1371/journal.pgen.1009078

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