Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice

Staphylococcus aureus infection of bone is challenging to treat because it colonizes the osteocyte lacuno-canalicular network (OLCN) of cortical bone. To elucidate factors involved in OLCN invasion and identify novel drug targets, we completed a hypothesis-driven screen of 24 S. aureus transposon in...

Descripción completa

Detalles Bibliográficos
Autores principales: Masters, Elysia A., de Mesy Bentley, Karen L., Gill, Ann Lindley, Hao, Stephanie P., Galloway, Chad A., Salminen, Alec T., Guy, Diamond R., McGrath, James L., Awad, Hani A., Gill, Steven R., Schwarz, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608983/
https://www.ncbi.nlm.nih.gov/pubmed/33091079
http://dx.doi.org/10.1371/journal.ppat.1008988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608983/
https://www.ncbi.nlm.nih.gov/pubmed/33091079
http://dx.doi.org/10.1371/journal.ppat.1008988

Ejemplares similares