Human 2-oxoglutarate-dependent oxygenases: nutrient sensors, stress responders, and disease mediators

Fe(II)/2-oxoglutarate (2OG)-dependent oxygenases are a conserved enzyme class that catalyse diverse oxidative reactions across nature. In humans, these enzymes hydroxylate a broad range of biological substrates including DNA, RNA, proteins and some metabolic intermediates. Correspondingly, members o...

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Detalles Bibliográficos
Autores principales: Fletcher, Sally C., Coleman, Mathew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609023/
https://www.ncbi.nlm.nih.gov/pubmed/32985654
http://dx.doi.org/10.1042/BST20190333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609023/
https://www.ncbi.nlm.nih.gov/pubmed/32985654
http://dx.doi.org/10.1042/BST20190333

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