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Biosynthesis of lanthionine-constrained agonists of G protein-coupled receptors

The conformation with which natural agonistic peptides interact with G protein-coupled receptor(s) (GPCR(s)) partly results from intramolecular interactions such as hydrogen bridges or is induced by ligand–receptor interactions. The conformational freedom of a peptide can be constrained by intramole...

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Detalles Bibliográficos
Autores principales: Moll, Gert N., Kuipers, Anneke, Rink, Rick, Bosma, Tjibbe, de Vries, Louwe, Namsolleck, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609037/
https://www.ncbi.nlm.nih.gov/pubmed/33125486
http://dx.doi.org/10.1042/BST20200427