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Breeder Diet Strategies for Generating Ttpa-Null and Wild-Type Mice with Low Vitamin E Status to Assess Neurological Outcomes

Studying vitamin E [α-tocopherol (α-T)] metabolism and function in the brain and other tissues requires an animal model with low α-T status, such as the transgenic α-T transfer protein (Ttpa)–null (Ttpa(−)(/)(−)) mouse model. Ttpa(+)(/)(−) dams can be used to produce Ttpa(−)(/)(−) and Ttpa(+/+)mice...

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Detalles Bibliográficos
Autores principales: Ranard, Katherine M, Kuchan, Matthew J, Erdman, John W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609157/
https://www.ncbi.nlm.nih.gov/pubmed/33173842
http://dx.doi.org/10.1093/cdn/nzaa155