Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann–Pick type C disease and Smith–Lemli–Opitz syndrome using light sheet microscopy

Lysosomal storage diseases are the most common cause of neurodegeneration in children. They are characterised at the cellular level by the accumulation of storage material within lysosomes. There are very limited therapeutic options, and the search for novel therapies has been hampered as few good s...

Descripción completa

Detalles Bibliográficos
Autores principales: Cook, Sophie R., Bladen, Cerys, Smith, Johanna, Maguire, Emily, Copner, Jordan, Fenn, Gareth D., Wager, Kim, Waller-Evans, Helen, Lloyd-Evans, Emyr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609433/
https://www.ncbi.nlm.nih.gov/pubmed/33079236
http://dx.doi.org/10.1007/s00418-020-01925-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609433/
https://www.ncbi.nlm.nih.gov/pubmed/33079236
http://dx.doi.org/10.1007/s00418-020-01925-2

Ejemplares similares