Enzyme kinetics and inhibition parameters of human leukocyte glucosylceramidase

Glucosylceramidase (GCase) is a lysosomal enzyme that catalyzes the cleavage of β-glucosidic linkage of glucocerebroside (GC) into glucose and ceramide; thereby, plays an essential function in the degradation of complex lipids and the turnover of cellular membranes. The growing list of 460 mutations...

Descripción completa

Detalles Bibliográficos
Autores principales: Karatas, Mesut, Dogan, Senol, Spahiu, Emrulla, Ašić, Adna, Bešić, Larisa, Turan, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609449/
https://www.ncbi.nlm.nih.gov/pubmed/33163670
http://dx.doi.org/10.1016/j.heliyon.2020.e05191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609449/
https://www.ncbi.nlm.nih.gov/pubmed/33163670
http://dx.doi.org/10.1016/j.heliyon.2020.e05191

Ejemplares similares