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Unveiling Druggable Pockets by Site-Specific Protein Modification: Beyond Antibody-Drug Conjugates
Site-specific modification approaches have been extensively employed in the development of protein-based technologies. In this field, stability and activity integrity are the envisioned features of chemically modified proteins. These methods are especially used in the design of antibody-drug conjuga...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609475/ https://www.ncbi.nlm.nih.gov/pubmed/33195086 http://dx.doi.org/10.3389/fchem.2020.586942 |