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Reactions of Medicinal Gold(III) Compounds With Proteins and Peptides Explored by Electrospray Ionization Mass Spectrometry and Complementary Biophysical Methods

Electrospray ionization mass spectrometry (ESI MS) is a powerful investigative tool to analyze the reactions of metallodrugs with proteins and peptides and characterize the resulting adducts. Here, we have applied this type of approach to four experimental anticancer gold(III) compounds for which ex...

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Detalles Bibliográficos
Autores principales: Massai, Lara, Zoppi, Carlotta, Cirri, Damiano, Pratesi, Alessandro, Messori, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609534/
https://www.ncbi.nlm.nih.gov/pubmed/33195070
http://dx.doi.org/10.3389/fchem.2020.581648