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IPEX as a Consequence of Alternatively Spliced FOXP3
The transcription factor FOXP3 controls the immunosuppressive program in CD4(+) T cells that is crucial for systemic immune regulation. Mutations of the single X-chromosomal FOXP3 gene in male individuals cause the inherited autoimmune disease immune dysregulation, polyendocrinopathy, enteropathy, a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609600/ https://www.ncbi.nlm.nih.gov/pubmed/33194927 http://dx.doi.org/10.3389/fped.2020.594375 |