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Demystifying the catalytic pathway of Mycobacterium tuberculosis isocitrate lyase

Pulmonary tuberculosis, caused by Mycobacterium tuberculosis, is one of the most persistent diseases leading to death in humans. As one of the key targets during the latent/dormant stage of M. tuberculosis, isocitrate lyase (ICL) has been a subject of interest for new tuberculosis therapeutics. In t...

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Detalles Bibliográficos
Autores principales: Ibeji, Collins U., Salleh, Nor Amirah Mohd, Sum, Jia Siang, Ch’ng, Angela Chiew Wen, Lim, Theam Soon, Choong, Yee Siew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609661/
https://www.ncbi.nlm.nih.gov/pubmed/33144641
http://dx.doi.org/10.1038/s41598-020-75799-8