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Targeting miR-18a sensitizes chondrocytes to anticytokine therapy to prevent osteoarthritis progression

Inflammation participates in the development of OA and targeting inflammatory signaling pathways is a potential strategy for OA treatment. IL-1β is one of the most important inflammatory factors to trigger the activation of NF-κB signaling and accelerate OA progression, whereas OA patients could har...

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Detalles Bibliográficos
Autores principales: Lian, Chengjie, Tao, Tianyu, Su, Peiqiang, Liao, Zhiheng, Wang, Xudong, Lei, Yiting, Zhao, Pei, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609664/
https://www.ncbi.nlm.nih.gov/pubmed/33144571
http://dx.doi.org/10.1038/s41419-020-03155-9