Cargando…

Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT‐20 and TtT/GF by affecting expression of MMP‐14 and ADAM12

Selective estrogen receptor modulators (SERMs) significantly affect survival and invasiveness of rodent pituitary adenoma (PA) cells. The impact of three clinically relevant SERMs (bazedoxifene, clomiphene, raloxifene) on invasiveness and on gene and protein expression of invasion‐related proteases...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhuo, Bartsch, Jörg W., Benzel, Julia, Lei, Ting, Nimsky, Christopher, Voellger, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609764/
https://www.ncbi.nlm.nih.gov/pubmed/33030286
http://dx.doi.org/10.1002/2211-5463.12999