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Cryo‐EM structure of fission yeast tetrameric α‐mannosidase Ams1

Fungal α‐mannosidase Ams1 and its mammalian homolog MAN2C1 hydrolyze terminal α‐linked mannoses in free oligosaccharides released from misfolded glycoproteins or lipid‐linked oligosaccharide donors. Ams1 is transported by selective autophagy into vacuoles. Here, we determine the tetrameric structure...

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Detalles Bibliográficos
Autores principales: Zhang, Jianxiu, Wang, Ying‐Ying, Du, Li‐Lin, Ye, Keqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609781/
https://www.ncbi.nlm.nih.gov/pubmed/32981237
http://dx.doi.org/10.1002/2211-5463.12988