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Knockout of cytochrome P450 1A1 enhances lipopolysaccharide‐induced acute lung injury in mice by targeting NF‐κB activation

Acute lung injury (ALI) is accompanied by overactivation of multiple pro‐inflammatory factors. Cytochrome P450 1A1 (CYP1A1) has been shown to aggravate lung injury in response to hyperoxia. However, the relationship between CYP1A1 and lipopolysaccharide (LPS)‐induced ALI is unknown. In this study, C...

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Detalles Bibliográficos
Autores principales: Tian, Li‐xing, Tang, Xin, Ma, Wei, Wang, Jing, Zhang, Wei, Liu, Kuan, Chen, Tao, Zhu, Jun‐yu, Liang, Hua‐ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609787/
https://www.ncbi.nlm.nih.gov/pubmed/32935470
http://dx.doi.org/10.1002/2211-5463.12977