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CircCOG8 Downregulation Contributes to the Compression-Induced Intervertebral Disk Degeneration by Targeting miR-182-5p and FOXO3

Circular RNAs (circRNAs) have been increasingly demonstrated to play critical roles in the pathogenesis of various human diseases. Intervertebral disk degeneration (IDD) is recognized as the major contributor to lower back pain, and mechanical stress is a predominant trigger for IDD. However, little...

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Detalles Bibliográficos
Autores principales: Xiang, Qian, Kang, Liang, Zhao, Kangcheng, Wang, Juntan, Hua, Wenbin, Song, Yu, Feng, Xiaobo, Li, Gaocai, Lu, Saideng, Wang, Kun, Yang, Cao, Zhang, Yukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609857/
https://www.ncbi.nlm.nih.gov/pubmed/33195225
http://dx.doi.org/10.3389/fcell.2020.581941