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Metronomic Celecoxib Therapy in Clinically Available Dosage Ablates Hepatocellular Carcinoma via Suppressing Cell Invasion, Growth, and Stemness in Pre-Clinical Models

OBJECTIVE: To investigate the anti-carcinogenic effect of metronomic Celecoxib (i.e., frequent administration in clinically available doses) against hepatocellular carcinoma (HCC) in the perspective of metastasis, spontaneous hepatocarcinogenesis, cancer invasion, proliferation, and stemness in vivo...

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Detalles Bibliográficos
Autores principales: Yeh, Chun-Chieh, Liao, Pei-Ying, Pandey, Sudhir, Yung, Su-Yung, Lai, Hsueh-Chou, Jeng, Long-Bin, Chang, Wei-Chun, Ma, Wen-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609882/
https://www.ncbi.nlm.nih.gov/pubmed/33194674
http://dx.doi.org/10.3389/fonc.2020.572861