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Noradrenaline Release from Locus Coeruleus Terminals in the Hippocampus Enhances Excitation-Spike Coupling in CA1 Pyramidal Neurons Via β-Adrenoceptors

Release of the neuromodulator noradrenaline signals salience during wakefulness, flagging novel or important experiences to reconfigure information processing and memory representations in the hippocampus. Noradrenaline is therefore expected to enhance hippocampal responses to synaptic input; howeve...

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Detalles Bibliográficos
Autores principales: Bacon, Travis J, Pickering, Anthony E, Mellor, Jack R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609922/
https://www.ncbi.nlm.nih.gov/pubmed/32607551
http://dx.doi.org/10.1093/cercor/bhaa159