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Tumor‐like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin‐induced insulin secretion in obese diabetes: A study of Zucker fatty diabetes mellitus rat

AIMS/INTRODUCTION: Pancreatic islets are heterogenous. To clarify the relationship between islet heterogeneity and incretin action in the islets, we studied gene expression and metabolic profiles of non‐large and enlarged islets of the Zucker fatty diabetes mellitus rat, an obese diabetes model, as...

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Detalles Bibliográficos
Autores principales: Hayami, Tomohide, Yokoi, Norihide, Yamaguchi, Takuro, Honda, Kohei, Murao, Naoya, Takahashi, Harumi, Wang, Shujie, Seino, Yusuke, Kamiya, Hideki, Yabe, Daisuke, Sweet, Ian R, Mizoguchi, Akira, Nakamura, Jiro, Seino, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610108/
https://www.ncbi.nlm.nih.gov/pubmed/32279428
http://dx.doi.org/10.1111/jdi.13272