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Tumor‐like features of gene expression and metabolic profiles in enlarged pancreatic islets are associated with impaired incretin‐induced insulin secretion in obese diabetes: A study of Zucker fatty diabetes mellitus rat
AIMS/INTRODUCTION: Pancreatic islets are heterogenous. To clarify the relationship between islet heterogeneity and incretin action in the islets, we studied gene expression and metabolic profiles of non‐large and enlarged islets of the Zucker fatty diabetes mellitus rat, an obese diabetes model, as...
Autores principales: | Hayami, Tomohide, Yokoi, Norihide, Yamaguchi, Takuro, Honda, Kohei, Murao, Naoya, Takahashi, Harumi, Wang, Shujie, Seino, Yusuke, Kamiya, Hideki, Yabe, Daisuke, Sweet, Ian R, Mizoguchi, Akira, Nakamura, Jiro, Seino, Susumu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610108/ https://www.ncbi.nlm.nih.gov/pubmed/32279428 http://dx.doi.org/10.1111/jdi.13272 |
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