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Transglutaminase-Mediated Cross-Linking of Tropoelastin to Fibrillin Stabilises the Elastin Precursor Prior to Elastic Fibre Assembly

Elastic fibres are essential components of all mammalian elastic tissues such as blood vessels, lung and skin, and are critically important for the mechanical properties they endow. The main components of elastic fibres are elastin and fibrillin, where correct formation of elastic fibres requires a...

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Detalles Bibliográficos
Autores principales: Lockhart-Cairns, Michael P., Newandee, Helena, Thomson, Jennifer, Weiss, Anthony S., Baldock, Clair, Tarakanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610145/
https://www.ncbi.nlm.nih.gov/pubmed/32898582
http://dx.doi.org/10.1016/j.jmb.2020.08.023