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Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers
[Image: see text] Transient permeability enhancers (PEs), such as caprylate, caprate, and salcaprozate sodium (SNAC), improve the bioavailability of poorly permeable macromolecular drugs. However, the effects are variable across individuals and classes of macromolecular drugs and biologics. Here, we...
Autores principales: | Hossain, Shakhawath, Joyce, Paul, Parrow, Albin, Jõemetsa, Silver, Höök, Fredrik, Larsson, Per, Bergström, Christel A. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610231/ https://www.ncbi.nlm.nih.gov/pubmed/32960068 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00668 |
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