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A p53/lnc‐Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance

Acetylation is a critical mechanism to modulate tumor‐suppressive activity of p53, but the causative roles of long non‐coding RNAs (lncRNAs) in p53 acetylation and their biological significance remain unexplored. Here, lncRNA LOC100294145 is discovered to be transactivated by p53 and is thus designa...

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Detalles Bibliográficos
Autores principales: Zhang, Li‐Zhen, Yang, Jin‐E, Luo, Yu‐Wei, Liu, Feng‐Ting, Yuan, Yun‐Fei, Zhuang, Shi‐Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610266/
https://www.ncbi.nlm.nih.gov/pubmed/33173727
http://dx.doi.org/10.1002/advs.202001364