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A p53/lnc‐Ip53 Negative Feedback Loop Regulates Tumor Growth and Chemoresistance
Acetylation is a critical mechanism to modulate tumor‐suppressive activity of p53, but the causative roles of long non‐coding RNAs (lncRNAs) in p53 acetylation and their biological significance remain unexplored. Here, lncRNA LOC100294145 is discovered to be transactivated by p53 and is thus designa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610266/ https://www.ncbi.nlm.nih.gov/pubmed/33173727 http://dx.doi.org/10.1002/advs.202001364 |